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1: Biochem Biophys Res Commun. 1999 Aug 2;261(2):225-32.
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Molecular mechanisms of copper homeostasis.

Camakaris J, Voskoboinik I, Mercer JF.

Department of Genetics, University of Melbourne, Parkville, Victoria, 3052, Australia. j.camakaris@genetics.unimelb.edu.au

Copper is an essential trace element which plays a pivotal role in cell physiology as it constitutes a core part of important cuproenzymes. Novel components of copper homeostasis in humans have been identified recently which have been characterised at the molecular level. These include copper-transporting P-type ATPases, Menkes and Wilson proteins, and copper chaperones. These findings have paved the way towards better understanding of the role of copper deficiency or copper toxicity in physiological and pathological conditions. Copyright 1999 Academic Press.

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PMID: 10425169 [PubMed - indexed for MEDLINE]