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Open Access Letter to the Editor

Reply to comment on Fisichella et al. (2012), “Intestinal toxicity evaluation of TiO2 degraded surface-treated nanoparticles: a combined physico-chemical and toxicogenomics approach in Caco-2 cells” by Faust et al.

Matthieu Fisichella1, Frédéric Bérenguer1, Gérard Steinmetz1, Mélanie Auffan23, Jérôme Rose23 and Odette Prat13*

Author Affiliations

1 CEA, IBEB, SBTN, LEPC, Bagnols-sur-Cèze, F-30207, France

2 CEREGE, UMR 7330 CNRS/ Aix-Marseille Université, ECCOREV, Europôle de l’Arbois, Aix-en-Provence, F-13545, France

3 International Consortium for the Environmental Implications of Nanotechnology (iCEINT), Aix-en-Provence, France

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Particle and Fibre Toxicology 2012, 9:39  doi:10.1186/1743-8977-9-39

Published: 1 November 2012

Abstract

In this response, we discuss the major differences that clearly distinguish our results from those mentioned by Faust et al. In particular, the experiments have been conducted on nanoparticles of different nature, what mainly explains the observed discrepancies. This is a reply to http://www.particleandfibretoxicology.com/content/pdf/1743-8977-9-39.pdf webcite.