Comparative toxicity of 24 manufactured nanoparticles in human alveolar epithelial and macrophage cell lines

doi:10.1186/1743-8977-6-14

Particle and Fibre Toxicology

Volume 6

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Lanone S
Rogerieux F
Geys J
Dupont A
Maillot-Marechal E
Boczkowski J
Lacroix G
Hoet P

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Rogerieux F
Geys J
Dupont A
Maillot-Marechal E
Boczkowski J
Lacroix G
Hoet P
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Comparative toxicity of 24 manufactured nanoparticles in human alveolar epithelial and macrophage cell lines

Sophie Lanone¹ , Françoise Rogerieux² , Jorina Geys³ , Aurélie Dupont¹ , Emmanuelle Maillot-Marechal² , Jorge Boczkowski¹^,4 , Ghislaine Lacroix² and Peter Hoet³

¹INSERM, Unité 700, Paris, France; Université Paris 7, Faculté de Médecine, site X. Bichat, Paris, France, and INSERM, Unité U955, Créteil, F-94010, France; Université Paris 12, Faculté de Médecine, Créteil, F-94010, France

²INERIS, Verneuil-en-Halatte, France

³Laboratory of Pneumology, Unit for Lung Toxicology, K.U. Leuven, Herestraat 49 O&N1 bus 706, 3000 Leuven, Belgium

⁴Assistance Publique-Hôpitaux de Paris, Hôpital Bichat, CIC 007, Paris, France

author email corresponding author email

Particle and Fibre Toxicology 2009, 6:14doi:10.1186/1743-8977-6-14


Published:	30 April 2009

Additional files

Additional File 1:

cell viability after 3 hours incubation on A549 cells, measured with Neutral Red assay. TC50, TC25 and TC75 values (μg/ml) obtained with NR assay, after 3 hours exposure of A549 cells, for each laboratory.

Format: DOCX Size: 98KB Download file

Additional File 2:

cell viability after 24 hours incubation on A549 cells, measured with Neutral Red assay. TC50, TC25 and TC75 values (μg/ml) obtained with MTT assay, after 24 hours exposure of THP-1 cells, for each laboratory.

Format: DOCX Size: 106KB Download file

Additional File 3:

cell viability after 3 hours incubation on A549 cells, measured with MTT assay. TC50, TC25 and TC75 values (μg/ml) obtained with MTT assay, after 3 hours exposure of A549 cells, for each laboratory.

Format: DOCX Size: 105KB Download file

Additional File 4:

cell viability after 24 hours incubation on A549 cells, measured with MTT assay. TC50, TC25 and TC75 values (μg/ml) obtained with MTT assay, after 24 hours exposure of A549 cells, for each laboratory.

Format: DOCX Size: 108KB Download file

Additional File 5:

cell viability after 3 hours incubation on THP-1 cells, measured with Neutral red assay. TC50, TC25 and TC75 values (μg/ml) obtained with NR assay, after 3 hours exposure of THP-1 cells, for each laboratory.

Format: DOCX Size: 106KB Download file

Additional File 6:

cell viability after 24 hours incubation on THP-1 cells, measured with Neutral red assay. TC50, TC25 and TC75 values (μg/ml) obtained with NR assay, after 24 hours exposure of THP-1 cells, for each laboratory.

Format: DOCX Size: 108KB Download file

Additional File 7:

cell viability after 3 hours incubation on THP-1 cells, measured with MTT assay. TC50, TC25 and TC75 values (μg/ml) obtained with MTT assay, after 3 hours exposure of THP-1 cells, for each laboratory.

Format: DOC Size: 71KB Download file

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