Figure 1.

A. TEM image of the as-received 70-nm rhodamine labeled SiO₂ particles. B. Fluorescence microscope image of human aortic endothelial cells (HAECs) treated with 70-nm rhodamine labeled SiO₂ particles (10 μg/cm²) for 24 hrs. 20× objective, 200× magnification. Red= SiO₂ particles; Blue = DAPI stained nucleus. C. Fluorescence image of cell lysate containing the 70-nm rhodamine labled particles. 20× objective, 200× magnification. D. TEM image of a dried aliquot of the final sample after cleanup for SdFFF containing 70-nm rhodamine labeled SiO₂ particles in dried residual material.