Table 7

Results of bacterial gene point mutation assay. Cerium oxide - nanoparticulate. Summary of mean revertant colonies obtained

Experiment 2
Substance
Dose Level (μg/plate)
TA100
TA1535
TA102
TA98
TA1537





Mean ± S.D.
Mean ± S.D.
Mean ± S.D.
Mean ± S.D.
Mean ± S.D.





(-S9)
(+S9)
(-S9)
(+S9)
(-S9)
(+S9)
(-S9)
(+S9)
(-S9)
(+S9)

DMSO
100 μl
97 ± 14
132 ± 8
28 ± 6
30 ± 11
394 ± 9
380 ± 25
21 ± 5
38 ± 7
12 ± 10
15 ± 6
Cerium Oxide Nano
50
99 ± 19
123 ± 17
32 ± 2
29 ± 5
359 ± 28
397 ± 39
21 ± 4
33 ± 10
12 ± 1
13 ± 6

150
98 ± 20
127 ± 10
35 ± 6
40 ± 6
361 ± 32
391 ± 32
22 ± 4
32 ± 2
14 ± 7
12 ± 4

500
84 ± 6
126 ± 11
35 ± 11
32 ± 4
382 ± 29
350 ± 7
21 ± 4
32 ± 5
14 ± 4
16 ± 4

1500 (F)
92 ± 8
133 ± 7
36 ± 8
36 ± 7
361 ± 43
313 ± 29
19 ± 5
37 ± 4
9 ± 3
12 ± 3

5000 (F+P+M)
95 ± 3
121 ± 22
28 ± 5
29 ± 3
371 ± 24
353 ± 36
19 ± 3
26 ± 3
9 ± 1
17 ± 2

S.D. Standard deviation

F Film

P Precipitate

M Manual Count

Park et al. Particle and Fibre Toxicology 2007 4:12   doi:10.1186/1743-8977-4-12