Table 6

Results of bacterial gene point mutation assay. Cerium oxide - nanoparticulate. Summary of mean revertant colonies obtained

Experiment 1


TA100
TA1535
TA102
TA98
TA1537



Substance
Dose Level (μg/plate)
Mean ± S.D.
Mean ± S.D.
Mean ± S.D.
Mean ± S.D.
Mean ± S.D.





(-S9)
(+S9)
(-S9)
(+S9)
(-S9)
(+S9)
(-S9)
(+S9)
(-S9)
(+S9)

DMSO
100 μl
118 ± 7
97 ± 13
39 ± 3
32 ± 6
347 ± 29
351 ± 4
28 ± 3
36 ± 7
13 ± 5
22 ± 2
Cerium Oxide Nano
50
100 ± 3
109 ± 17
37 ± 2
29 ± 13
356 ± 10
363 ± 25
23 ± 5
36 ± 2
11 ± 5
18 ± 4

150
88 ± 13
115 ± 9
40 ± 3
36 ± 1
360 ± 13
381 ± 20
25 ± 6
35 ± 6
12 ± 5
15 ± 5

500
84 ± 16
114 ± 20
33 ± 3
36 ± 3
377 ± 12
350 ± 17
26 ± 6
35 ± 7
14 ± 5
17 ± 4

1500 (F)
101 ± 13
115 ± 8
28 ± 4
32 ± 9
343 ± 38
330 ± 17
22 ± 3
35 ± 1
14 ± 4
24 ± 2

5000 (F+M+P)
101 ± 4
113 ± 7
39 ± 3
38 ± 2
343 ± 16
332 ± 14
23 ± 4
37 ± 4
12 ± 2
20 ± 5

Park et al. Particle and Fibre Toxicology 2007 4:12   doi:10.1186/1743-8977-4-12