Table 5

Results of bacterial gene point mutation assay. Cerium oxide – non-nanoparticulate. Summary of mean revertant colonies obtained

Experiment 2
Substance
Dose Level (μg/plate)
TA100
TA1535
TA102
TA98
TA1537





Mean ± S.D.
Mean ± S.D.
Mean ± S.D.
Mean ± S.D.
Mean ± S.D.





(-S9)
(+S9)
(-S9)
(+S9)
(-S9)
(+S9)
(-S9)
(+S9)
(-S9)
(+S9)

DMSO
100 μl
93 ± 16
105 ± 13
27 ± 7
9 ± 1
345 ± 17
374 ± 13
20 ± 3
27 ± 7
8 ± 3
13 ± 4
Cerium Oxide Non-nano
50
87 ± 10
115 ± 10
32 ± 2
11 ± 7
349 ± 42
352 ± 31
16 ± 7
23 ± 2
15 ± 4
19 ± 4

150
95 ± 4
91 ± 8
28 ± 7
14 ± 2
343 ± 20
397 ± 21
20 ± 3
23 ± 2
8 ± 4
19 ± 5

500
94 ± 13
89 ± 4
37 ± 5
9 ± 1
349 ± 27
364 ± 23
18 ± 2
29 ± 3
9 ± 1
17 ± 3

1500
82 ± 2
99 ± 2
33 ± 12
9 ± 3
351 ± 22
380 ± 10
17 ± 2
28 ± 4
8 ± 4
21 ± 6

5000
107 ± 2
97 ± 13
26 ± 4
10 ± 2
350 ± 49
382 ± 21
18 ± 4
23 ± 6
15 ± 5
19 ± 3

S.D. Standard deviation

Park et al. Particle and Fibre Toxicology 2007 4:12   doi:10.1186/1743-8977-4-12