Table 4

Results of bacterial gene point mutation assay. Cerium oxide – non-nanoparticulate. Summary of mean revertant colonies obtained
Experiment 1
Substance
 Dose Level (μg/plate)
 TA100
 TA1535
 TA102
 TA98
 TA1537




Mean ± S.D.
 Mean ± S.D.
 Mean ± S.D.
 Mean ± S.D.
 Mean ± S.D.




(-S9)
 (+S9)
 (-S9)
 (+S9)
 (-S9)
 (+S9)
 (-S9)
 (+S9)
 (-S9)
 (+S9)
DMSO
 100 μl
 83 ± 7
 64 ± 5
 40 ± 2
 12 ± 2
 309 ± 24
 333 ± 29
 21 ± 5
 26 ± 4
 10 ± 2
 17 ± 3
Cerium Oxide Non-nano
 50
 85 ± 12
 73 ± 11
 37 ± 5
 13 ± 1
 333 ± 28
 361 ± 29
 19 ± 4
 29 ± 2
 12 ± 2
 19 ± 6

150
 96 ± 7
 70 ± 9
 34 ± 3
 11 ± 2
 341 ± 21
 359 ± 7
 19 ± 3
 29 ± 3
 13 ± 3
 18 ± 3

500
 80 ± 12
 76 ± 10
 35 ± 7
 11 ± 2
 345 ± 9
 367 ± 11
 22 ± 7
 29 ± 6
 13 ± 3
 20 ± 4

1500
 69 ± 10
 75 ± 11
 34 ± 2
 13 ± 6
 338 ± 10
 350 ± 26
 16 ± 2
 25 ± 3
 12 ± 5
 21 ± 5

5000
 84 ± 7
 73 ± 9
 36 ± 3
 10 ± 2
 313 ± 21
 354 ± 14
 16 ± 4
 31 ± 4
 11 ± 1
 22 ± 1

Park et al. Particle and Fibre Toxicology 2007 4:12   doi:10.1186/1743-8977-4-12