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Semiquantitative score of cytotoxic response for BS EN ISO 10993-5 Cytotoxicity Test |
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| Grade |
Cytotoxicity/Reactivity |
Description of Cytotoxicity/Reactivity Zone |
|
|
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| 0 |
None |
No detectable zone around or under specimen |
| 1 |
Slight |
Some malformed or degenerated cells |
| 2 |
Mild |
Zone limited to area under specimen |
| 3 |
Moderate |
Zone extends 0.5 to 1.0 cm beyond specimen |
| 4 |
Severe |
Zone extends greater than 1.0 cm beyond specimen but does not involve entire dish |
Park et al. Particle and Fibre Toxicology 2007 4:12 doi:10.1186/1743-8977-4-12 |
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