Particle and Fibre Toxicology

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		Research Multi-walled carbon nanotubes induce COX-2 and iNOS expression via MAP Kinase-dependent and - independent mechanisms in mouse RAW264.7 macrophages Jong Kwon Lee, Brian C. Sayers, Kyung-Soo Chun, Huei-Chen Lao, Jeanette K. Shipley-Phillips, James C. Bonner, Robert Langenbach Particle and Fibre Toxicology 2012, 9:14 (9 May 2012) Abstract \| Provisional PDF \| PubMed
		Review A short history of the toxicology of inhaled particles Ken Donaldson, Anthony Seaton Particle and Fibre Toxicology 2012, 9:13 (6 May 2012) Abstract \| Provisional PDF \| PubMed
		Research Effects of wood smoke particles from wood-burning stoves on the respiratory health of atopic humans Ingunn S. Riddervold, Jakob Hjort Bønløkke, Anna-Carin Olin, Therese Koops Grønborg, Vivi Schlünssen, Kristin Skogstrand, David M. Hougaard, Andreas Massling, Torben Sigsgaard Particle and Fibre Toxicology 2012, 9:12 (30 April 2012) Abstract \| Provisional PDF \| PubMed
		Research Cytotoxicity and cellular uptake of tri-block copolymer nanoparticles with different size and surface characteristics Sourav Bhattacharjee, Dmitry Ershov, Kleanthis Fytianos, Jasper vd Gucht, Gerrit M Alink, Ivonne MCM Rietjens, Antonius TM Marcelis, Han Zuilhof Particle and Fibre Toxicology 2012, 9:11 (30 April 2012) Abstract \| Provisional PDF \| PubMed
		Research Factoring-in agglomeration of carbon nanotubes and nanofibers for better prediction of their toxicity versus asbestos Ashley R Murray, Elena R Kisin, Alexey V Tkach, Naveena Yanamala, Robert R Mercer, Shih-Houng Young, Bengt Fadeel, Valerian E Kagan, Anna A Shvedova Particle and Fibre Toxicology 2012, 9:10 (10 April 2012) Abstract \| Provisional PDF \| PubMed
		Research Diesel exhaust particulate induces pulmonary and systemic inflammation in rats without impairing endothelial function ex vivo or in vivo Sarah Robertson, Gillian A Gray, Rodger Duffin, Steven G McLean, Catherine A Shaw, Patrick WF Hadoke, David E Newby, Mark R Miller Particle and Fibre Toxicology 2012, 9:9 (5 April 2012) Abstract \| Provisional PDF \| PubMed
		Research The mechanism of pleural inflammation by long carbon nanotubes: interaction of long fibres with macrophages stimulates them to amplify pro-inflammatory responses in mesothelial cells Fiona A Murphy, Anja Schinwald, Craig A Poland, Ken Donaldson Particle and Fibre Toxicology 2012, 9:8 (3 April 2012) Abstract \| Full text \| PDF \| PubMed
		Research Controlled human wood smoke exposure: oxidative stress, inflammation and microvascular function Lykke Forchhammer, Peter Moller, Ingunn S Riddervold, Jakob Bonlokke, Andreas Massling, Torben Sigsgaard, Steffen Loft Particle and Fibre Toxicology 2012, 9:7 (27 March 2012) Abstract \| Provisional PDF \| PubMed
		Research Differences in gene expression and cytokine production by crystalline vs. amorphous silica in human lung epithelial cells Timothy N Perkins, Arti Shukla, Paul M Peeters, Jeremy L Steinbacher, Christopher C Landry, Sherrill A Lathrop, Chad Steele, Niki L Reynaert, Emiel FM Wouters, Brooke T Mossman Particle and Fibre Toxicology 2012, 9:6 (2 February 2012) Abstract \| Full text \| PDF \| PubMed
		Research Carbon black nanoparticle instillation induces sustained inflammation and genotoxicity in mouse lung and liver Julie A Bourdon, Anne T Saber, Nicklas R Jacobsen, Keld A Jensen, Anne M Madsen, Jacob S Lamson, Håkan Wallin, Peter Møller, Steffen Loft, Carole L Yauk, Ulla B Vogel Particle and Fibre Toxicology 2012, 9:5 (2 February 2012) Abstract \| Full text \| PDF \| PubMed
		Research Nanotitanium dioxide toxicity in mouse lung is reduced in sanding dust from paint Anne Saber, Nicklas Jacobsen, Alicia Mortensen, Józef Szarek, Petra Jackson, Anne Madsen, Keld Jensen, Ismo K Koponen, Gunnar Brunborg, Kristine Gützkow, Ulla Vogel, Håkan Wallin Particle and Fibre Toxicology 2012, 9:4 (2 February 2012) Abstract \| Full text \| PDF \| PubMed
		Research Amorphous silica nanoparticles size-dependently aggravate atopic dermatitis-like skin lesions following an intradermal injection Toshiro Hirai, Tomoaki Yoshikawa, Hiromi Nabeshi, Tokuyuki Yoshida, Saeko Tochigi, Ko-ichi Ichihashi, Miyuki Uji, Takanori Akase, Kazuya Nagano, Yasuhiro Abe, Haruhiko Kamada, Norio Itoh, Shin-ichi Tsunoda, Yasuo Yoshioka, Yasuo Tsutsumi Particle and Fibre Toxicology 2012, 9:3 (2 February 2012) Abstract \| Full text \| PDF \| PubMed
		Research A mixture of anatase and rutile TiO₂nanoparticles induces histamine secretion in mast cells Eric Y Chen, Maria Garnica, Yung-Chen Wang, Alexander J Mintz, Chi-Shuo Chen, Wei-Chun Chin Particle and Fibre Toxicology 2012, 9:2 (19 January 2012) Abstract \| Full text \| PDF \| PubMed
		Research Global gene expression changes in human embryonic lung fibroblasts induced by organic extracts from respirable air particles Helena Líbalová, Kateřina Uhlířová, Jiří Kléma, Miroslav Machala, Radim J Šrám, Miroslav Ciganek, Jan Topinka Particle and Fibre Toxicology 2012, 9:1 (12 January 2012) Abstract \| Full text \| PDF \| PubMed
		Research Shape matters: effects of silver nanospheres and wires on human alveolar epithelial cells Linda C Stoehr, Edgar Gonzalez, Andreas Stampfl, Eudald Casals, Albert Duschl, Victor Puntes, Gertie J Oostingh Particle and Fibre Toxicology 2011, 8:36 (30 December 2011) Abstract \| Full text \| PDF \| PubMed
		Commentary Historical perspective fifty years of particles: a personal retrospect Anthony Seaton Particle and Fibre Toxicology 2011, 8:35 (29 December 2011) Abstract \| Full text \| PDF \| PubMed
		Commentary Obituary: Dr John MG Davis PhD, DSc, FRCPath Anthony Seaton Particle and Fibre Toxicology 2011, 8:34 (21 December 2011) Abstract \| Full text \| PDF \| PubMed
		Research Acute toxicity study of tilmicosin-loaded hydrogenated castor oil-solid lipid nanoparticles Shuyu Xie, Fenghua Wang, Yan Wang, Luyan Zhu, Zhao Dong, Xiaofang Wang, Xihe Li, WenZhong Zhou Particle and Fibre Toxicology 2011, 8:33 (20 November 2011) Abstract \| Full text \| PDF \| PubMed
		Research Modest effect on plaque progression and vasodilatory function in atherosclerosis-prone mice exposed to nanosized TiO₂ Lone Mikkelsen, Majid Sheykhzade, Keld A Jensen, Anne T Saber, Nicklas R Jacobsen, Ulla Vogel, Håkan Wallin, Steffen Loft, Peter Møller Particle and Fibre Toxicology 2011, 8:32 (10 November 2011) Abstract \| Full text \| PDF \| PubMed
		Research Contrasting macrophage activation by fine and ultrafine titanium dioxide particles is associated with different uptake mechanisms Agnes M Scherbart, Julia Langer, Alexey Bushmelev, Damiёn van Berlo, Petra Haberzettl, Frederik-Jan van Schooten, Annette M Schmidt, Christine R Rose, Roel PF Schins, Catrin Albrecht Particle and Fibre Toxicology 2011, 8:31 (13 October 2011) Abstract \| Full text \| PDF \| PubMed
		Research Comparison of particle-exposure triggered pulmonary and systemic inflammation in mice fed with three different diets Alexander A Götz, Jan Rozman, Heiko G Rödel, Helmut Fuchs, Valérie Gailus-Durner, Martin Hrabě de Angelis, Martin Klingenspor, Tobias Stoeger Particle and Fibre Toxicology 2011, 8:30 (27 September 2011) Abstract \| Full text \| PDF \| PubMed
		Research Effects of copper nanoparticle exposure on host defense in a murine pulmonary infection model Jong Sung Kim, Andrea Adamcakova-Dodd, Patrick T O'Shaughnessy, Vicki H Grassian, Peter S Thorne Particle and Fibre Toxicology 2011, 8:29 (24 September 2011) Abstract \| Full text \| PDF \| PubMed
		Research Carbon-nanoparticle-triggered acute lung inflammation and its resolution are not altered in PPARγ-defective (P465L) mice Alexander A Götz, Antonio Vidal-Puig, Heiko G Rödel, Martin de Angelis, Tobias Stoeger Particle and Fibre Toxicology 2011, 8:28 (20 September 2011) Abstract \| Full text \| PDF \| PubMed
		Research Progressive severe lung injury by zinc oxide nanoparticles; the role of Zn²⁺dissolution inside lysosomes Wan-Seob Cho, Rodger Duffin, Sarah EM Howie, Chris J Scotton, William AH Wallace, William MacNee, Mark Bradley, Ian L Megson, Ken Donaldson Particle and Fibre Toxicology 2011, 8:27 (6 September 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research In vitro toxicity of particulate matter (PM) collected at different sites in the Netherlands is associated with PM composition, size fraction and oxidative potential - the RAPTES project Maaike Steenhof, Ilse Gosens, Maciej Strak, Krystal J Godri, Gerard Hoek, Flemming R Cassee, Ian S Mudway, Frank J Kelly, Roy M Harrison, Erik Lebret, Bert Brunekreef, Nicole AH Janssen, Raymond HH Pieters Particle and Fibre Toxicology 2011, 8:26 (2 September 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Medicine \| F1000 Biology

	All
		Research Multi-walled carbon nanotubes induce COX-2 and iNOS expression via MAP Kinase-dependent and - independent mechanisms in mouse RAW264.7 macrophages Jong Kwon Lee, Brian C. Sayers, Kyung-Soo Chun, Huei-Chen Lao, Jeanette K. Shipley-Phillips, James C. Bonner, Robert Langenbach Particle and Fibre Toxicology 2012, 9:14 (9 May 2012) Abstract \| Provisional PDF \| PubMed
		Review A short history of the toxicology of inhaled particles Ken Donaldson, Anthony Seaton Particle and Fibre Toxicology 2012, 9:13 (6 May 2012) Abstract \| Provisional PDF \| PubMed
		Research Effects of wood smoke particles from wood-burning stoves on the respiratory health of atopic humans Ingunn S. Riddervold, Jakob Hjort Bønløkke, Anna-Carin Olin, Therese Koops Grønborg, Vivi Schlünssen, Kristin Skogstrand, David M. Hougaard, Andreas Massling, Torben Sigsgaard Particle and Fibre Toxicology 2012, 9:12 (30 April 2012) Abstract \| Provisional PDF \| PubMed
		Research Cytotoxicity and cellular uptake of tri-block copolymer nanoparticles with different size and surface characteristics Sourav Bhattacharjee, Dmitry Ershov, Kleanthis Fytianos, Jasper vd Gucht, Gerrit M Alink, Ivonne MCM Rietjens, Antonius TM Marcelis, Han Zuilhof Particle and Fibre Toxicology 2012, 9:11 (30 April 2012) Abstract \| Provisional PDF \| PubMed
		Research Factoring-in agglomeration of carbon nanotubes and nanofibers for better prediction of their toxicity versus asbestos Ashley R Murray, Elena R Kisin, Alexey V Tkach, Naveena Yanamala, Robert R Mercer, Shih-Houng Young, Bengt Fadeel, Valerian E Kagan, Anna A Shvedova Particle and Fibre Toxicology 2012, 9:10 (10 April 2012) Abstract \| Provisional PDF \| PubMed
		Research Diesel exhaust particulate induces pulmonary and systemic inflammation in rats without impairing endothelial function ex vivo or in vivo Sarah Robertson, Gillian A Gray, Rodger Duffin, Steven G McLean, Catherine A Shaw, Patrick WF Hadoke, David E Newby, Mark R Miller Particle and Fibre Toxicology 2012, 9:9 (5 April 2012) Abstract \| Provisional PDF \| PubMed
		Research The mechanism of pleural inflammation by long carbon nanotubes: interaction of long fibres with macrophages stimulates them to amplify pro-inflammatory responses in mesothelial cells Fiona A Murphy, Anja Schinwald, Craig A Poland, Ken Donaldson Particle and Fibre Toxicology 2012, 9:8 (3 April 2012) Abstract \| Full text \| PDF \| PubMed
		Research Controlled human wood smoke exposure: oxidative stress, inflammation and microvascular function Lykke Forchhammer, Peter Moller, Ingunn S Riddervold, Jakob Bonlokke, Andreas Massling, Torben Sigsgaard, Steffen Loft Particle and Fibre Toxicology 2012, 9:7 (27 March 2012) Abstract \| Provisional PDF \| PubMed
		Research Differences in gene expression and cytokine production by crystalline vs. amorphous silica in human lung epithelial cells Timothy N Perkins, Arti Shukla, Paul M Peeters, Jeremy L Steinbacher, Christopher C Landry, Sherrill A Lathrop, Chad Steele, Niki L Reynaert, Emiel FM Wouters, Brooke T Mossman Particle and Fibre Toxicology 2012, 9:6 (2 February 2012) Abstract \| Full text \| PDF \| PubMed
		Research Carbon black nanoparticle instillation induces sustained inflammation and genotoxicity in mouse lung and liver Julie A Bourdon, Anne T Saber, Nicklas R Jacobsen, Keld A Jensen, Anne M Madsen, Jacob S Lamson, Håkan Wallin, Peter Møller, Steffen Loft, Carole L Yauk, Ulla B Vogel Particle and Fibre Toxicology 2012, 9:5 (2 February 2012) Abstract \| Full text \| PDF \| PubMed
		Research Nanotitanium dioxide toxicity in mouse lung is reduced in sanding dust from paint Anne Saber, Nicklas Jacobsen, Alicia Mortensen, Józef Szarek, Petra Jackson, Anne Madsen, Keld Jensen, Ismo K Koponen, Gunnar Brunborg, Kristine Gützkow, Ulla Vogel, Håkan Wallin Particle and Fibre Toxicology 2012, 9:4 (2 February 2012) Abstract \| Full text \| PDF \| PubMed
		Research Amorphous silica nanoparticles size-dependently aggravate atopic dermatitis-like skin lesions following an intradermal injection Toshiro Hirai, Tomoaki Yoshikawa, Hiromi Nabeshi, Tokuyuki Yoshida, Saeko Tochigi, Ko-ichi Ichihashi, Miyuki Uji, Takanori Akase, Kazuya Nagano, Yasuhiro Abe, Haruhiko Kamada, Norio Itoh, Shin-ichi Tsunoda, Yasuo Yoshioka, Yasuo Tsutsumi Particle and Fibre Toxicology 2012, 9:3 (2 February 2012) Abstract \| Full text \| PDF \| PubMed
		Research A mixture of anatase and rutile TiO₂nanoparticles induces histamine secretion in mast cells Eric Y Chen, Maria Garnica, Yung-Chen Wang, Alexander J Mintz, Chi-Shuo Chen, Wei-Chun Chin Particle and Fibre Toxicology 2012, 9:2 (19 January 2012) Abstract \| Full text \| PDF \| PubMed
		Research Global gene expression changes in human embryonic lung fibroblasts induced by organic extracts from respirable air particles Helena Líbalová, Kateřina Uhlířová, Jiří Kléma, Miroslav Machala, Radim J Šrám, Miroslav Ciganek, Jan Topinka Particle and Fibre Toxicology 2012, 9:1 (12 January 2012) Abstract \| Full text \| PDF \| PubMed
		Research Shape matters: effects of silver nanospheres and wires on human alveolar epithelial cells Linda C Stoehr, Edgar Gonzalez, Andreas Stampfl, Eudald Casals, Albert Duschl, Victor Puntes, Gertie J Oostingh Particle and Fibre Toxicology 2011, 8:36 (30 December 2011) Abstract \| Full text \| PDF \| PubMed
		Commentary Historical perspective fifty years of particles: a personal retrospect Anthony Seaton Particle and Fibre Toxicology 2011, 8:35 (29 December 2011) Abstract \| Full text \| PDF \| PubMed
		Commentary Obituary: Dr John MG Davis PhD, DSc, FRCPath Anthony Seaton Particle and Fibre Toxicology 2011, 8:34 (21 December 2011) Abstract \| Full text \| PDF \| PubMed
		Research Acute toxicity study of tilmicosin-loaded hydrogenated castor oil-solid lipid nanoparticles Shuyu Xie, Fenghua Wang, Yan Wang, Luyan Zhu, Zhao Dong, Xiaofang Wang, Xihe Li, WenZhong Zhou Particle and Fibre Toxicology 2011, 8:33 (20 November 2011) Abstract \| Full text \| PDF \| PubMed
		Research Modest effect on plaque progression and vasodilatory function in atherosclerosis-prone mice exposed to nanosized TiO₂ Lone Mikkelsen, Majid Sheykhzade, Keld A Jensen, Anne T Saber, Nicklas R Jacobsen, Ulla Vogel, Håkan Wallin, Steffen Loft, Peter Møller Particle and Fibre Toxicology 2011, 8:32 (10 November 2011) Abstract \| Full text \| PDF \| PubMed
		Research Contrasting macrophage activation by fine and ultrafine titanium dioxide particles is associated with different uptake mechanisms Agnes M Scherbart, Julia Langer, Alexey Bushmelev, Damiёn van Berlo, Petra Haberzettl, Frederik-Jan van Schooten, Annette M Schmidt, Christine R Rose, Roel PF Schins, Catrin Albrecht Particle and Fibre Toxicology 2011, 8:31 (13 October 2011) Abstract \| Full text \| PDF \| PubMed
		Research Comparison of particle-exposure triggered pulmonary and systemic inflammation in mice fed with three different diets Alexander A Götz, Jan Rozman, Heiko G Rödel, Helmut Fuchs, Valérie Gailus-Durner, Martin Hrabě de Angelis, Martin Klingenspor, Tobias Stoeger Particle and Fibre Toxicology 2011, 8:30 (27 September 2011) Abstract \| Full text \| PDF \| PubMed
		Research Effects of copper nanoparticle exposure on host defense in a murine pulmonary infection model Jong Sung Kim, Andrea Adamcakova-Dodd, Patrick T O'Shaughnessy, Vicki H Grassian, Peter S Thorne Particle and Fibre Toxicology 2011, 8:29 (24 September 2011) Abstract \| Full text \| PDF \| PubMed
		Research Carbon-nanoparticle-triggered acute lung inflammation and its resolution are not altered in PPARγ-defective (P465L) mice Alexander A Götz, Antonio Vidal-Puig, Heiko G Rödel, Martin de Angelis, Tobias Stoeger Particle and Fibre Toxicology 2011, 8:28 (20 September 2011) Abstract \| Full text \| PDF \| PubMed
		Research Progressive severe lung injury by zinc oxide nanoparticles; the role of Zn²⁺dissolution inside lysosomes Wan-Seob Cho, Rodger Duffin, Sarah EM Howie, Chris J Scotton, William AH Wallace, William MacNee, Mark Bradley, Ian L Megson, Ken Donaldson Particle and Fibre Toxicology 2011, 8:27 (6 September 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research In vitro toxicity of particulate matter (PM) collected at different sites in the Netherlands is associated with PM composition, size fraction and oxidative potential - the RAPTES project Maaike Steenhof, Ilse Gosens, Maciej Strak, Krystal J Godri, Gerard Hoek, Flemming R Cassee, Ian S Mudway, Frank J Kelly, Roy M Harrison, Erik Lebret, Bert Brunekreef, Nicole AH Janssen, Raymond HH Pieters Particle and Fibre Toxicology 2011, 8:26 (2 September 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Medicine \| F1000 Biology